Rodríguez-Beltrán, Jerónimo; Sørum, Vidar; Toll-Riera, Macarena; de la Vega, Carmen; Peña-Miller, Rafael; San Millán, Álvaro (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-22)
Mobile genetic elements (MGEs), such as plasmids, promote bacterial evolution through horizontal gene transfer (HGT). However, the rules governing the repertoire of traits encoded on MGEs remain unclear. In this study, we uncovered the central role of genetic dominance shaping genetic cargo in MGEs, using antibiotic resistance as a model system. MGEs are typically present in more than one copy per ...